SS-31
10 in stock
Lots & Certificates
Each released lot has one certificate of analysis. Check the lot number printed on your vial against this list.
Product Information
It is not for human consumption. Use only in a laboratory setting by qualified personnel. The FDA has not evaluated this product for safety or efficacy. Any other use is strictly prohibited.
SS-31 Peptide Specifications
SS-31 is supplied by Alma Research Labs as a catalogued research material in 10 mg.
SS-31 is the tetrapeptide elamipretide, defined by D-Arg, 2,6-dimethyl-L-tyrosine and a C-terminal amide. Free peptide, hydrochloride, acetate and TFA forms require separate formula and mass treatment; the exact counter-ion must be confirmed [1–3].
A Szeto-Schiller (SS) peptide that selectively targets cardiolipin in the inner mitochondrial membrane, exhibiting antioxidant and mitochondrial-protective effects.
Chemical Properties and Registry Information
| Property | Value |
| Name and synonyms | Elamipretide, MTP-131, Bendavia |
| Material category | Mitochondrial-Targeting Peptide |
| Sequence | H-D-Arg-Dmt-Lys-Phe-NH2 |
| Molecular formula | C32H49N9O5 |
| Average molecular mass | 639.8 g/mol |
| CAS Registry Number | 736992-21-5 |
| PubChem CID | CID 16132533 |
| Structural features | Aromatic-cationic tetrapeptide with an N-terminal D-Arginine, a 2′,6′-dimethyltyrosine (Dmt) residue, and a C-terminal phenylalaninamide. |
| Appearance | White to off-white lyophilised powder |
| Solubility | Readily soluble in sterile or bacteriostatic water. |
| Physical form | Catalogue vial; exact salt/counter-ion and excipients are batch-specific and must be verified in the CoA and SDS. |
Note: Registry values apply only to the specific molecular entity, sequence, termini, and material form. Batch records take precedence over family-level literature identifiers.
Research Background and Published Evidence
Published research
Appropriate contexts include peptide–lipid-bilayer interaction, membrane-surface electrostatics, isolated or ex-vivo mitochondrial assays, and exact-form analytical characterization. These models support mechanistic investigation, not a product-performance claim [2,3].
Current scientific understanding
Research and regulatory documents for separately manufactured elamipretide products do not authenticate this lot. Membrane or mitochondrial observations do not establish safety, efficacy, or suitability for human or veterinary use.
Elamipretide received U.S. accelerated approval in 2025.
Technical Comparison
| Aspect | This catalogue material | Comparator |
| Identity | SS-31/elamipretide: H-D-Arg-Dmt-Lys-Phe-NH₂ | SS-20, a different Szeto–Schiller peptide lacking Dmt |
| Structural distinction | Contains the redox-active aromatic Dmt residue | Different sequence and physicochemical reference profile |
| Analytical implication | Confirm D-residue stereochemistry, Dmt, and C-terminal amide | Requires its own exact-form reference standard |
Quality and Testing
Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot, or similarly named material must not be treated as evidence for this product.
Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin, and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.
Laboratory Handling and Storage
Store and handle only under the conditions stated on the product label, batch CoA, and SDS provided by Alma Research Labs. Keep the container secured, correctly identified, and protected from contamination. Do not infer storage, solvent compatibility, or stability from a related compound.
Laboratory preparation, analytical-method selection, risk assessment, personal protective equipment, and waste disposal should follow the applicable SDS and the institution’s approved procedures.
Regulatory and Legal Status
Research-use notice: This material is supplied exclusively by Alma Research Labs for laboratory research by qualified professionals and is not intended for human or veterinary use. Purchasers are responsible for compliance with applicable local requirements.
